Oral Acanthosis Nigricans (AN) and Leser-Trelat sign (LT) in metastatic serous ovarian carcinoma: case report and review of literature
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چکیده
This article discusses the rarity of oral ANand the ongoing debate of LT as a paraneoplastic syndrome. Two literature reviews were carried out on malignant oral AN; and on reported LT cases between 2005 and 2016. It highlights the importance of clinical oral examination and emphasizes all clinicians to investigate for internal malignancies especially in cases with the coexistence of multiple cutaneous markers. Keywords
منابع مشابه
گزارش یک مورد آکانتوزیزنیگریکانس ، تریپل پالم و علامت لسرترلات در بیماری با کارسینوئید تومور
Acanthosis nigricans (AN), Tripe palm (TP) and sign of lesser trelat (LT) are rare dermatoses which are often seen with malignant conditions. Acanthosis nigricans occurs both on the skin and mucus membranes as velvety hyper pigmented lesions in the flexors and around the neck, or papillomatous and verrucous lesions on the lips and buccal mucosa. These para neoplastic dermatoses are generally li...
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The skin is a unique marker for malignancy as these cutaneous manifestation not only often precede the development of other symptoms, but also often cause patients to seek medical attention sooner than they would for other symptoms. Common cutaneous markers for malignancy include: acanthosis nigricans, carcinoid syndrome, Leser-Trelat sign, and necrolytic migratory erythema. Although these skin...
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Acanthosis nigricans is a common dermatosis and is most often associated with benign conditions, such as insulin resistance. It is rare as a paraneoplastic marker. As such, it is characterized by sudden onset and rapid dissemination of velvety and hyperchromic skin lesions. The term "tripe palm" refers to exaggeration of the palmar ridge pattern, which resembles the internal surface of the bovi...
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تاریخ انتشار 2017